detection of the most common microorganisms and their resistance against anti-microbials in intubated patients in an icu in kerman, iran

نویسندگان

farhad sarafzadeh pharmaceutics research center and faculty of medicine, kerman university of medical science, kerman, iran.

seyed mojtaba sohrevardi kerman neuroscience research center and faculty of pharmacy, kerman university of medical science, kerman, iran.

maryam gharehghozli faculty of medicine, kerman university of medical science, kerman, iran

mehdi ahmadinejad faculty of medicine, kerman university of medical science, kerman, iran

چکیده

the purpose of this study was to determine the prevalence of anti-microbial resistance in intubated patients in intensive care unit (icu) of bahonar hospital in kerman province, iran during the year 2008. tracheal samples were obtained from 111 intubated patients in the icu by broncoalveolar lavage method. amikacin, ceftazidim and imipenem were used to evaluate antibiotic susceptibility. for detecting anti-microbial susceptibility, minimum inhibitory concentration method were used. colony counts equal or more than 104 microorganisms/ml were considered resistant. overall we obtained positive tracheal cultures from 32 patients (29%) out of 111 intubated ones. the most common micro organisms isolated were klebsiella (90.6%), acinetobacter (28.1%) and pseudomonas (21.9%). the results showed that the most common resistance was against to ceftazidim. the susceptibility of klebsiella in tracheal cultures to the antibiotics was only 5%. e. coli in both sexes was 100% resistant to the tested antibiotics. in the icu, there was a very big problem concerning antibiotic resistance. most of the isolated microorganisms were resistant to both the old and the new antibiotics. it may be related to the inappropriate use of antibiotics, bacterial contamination of enteral feeding and infection transmission by medical staff or instruments.

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Detection of the Most Common Microorganisms and Their Resistance against Anti-microbials in Intubated Patients in an ICU in Kerman, Iran

The purpose of this study was to determine the prevalence of anti-microbial resistance in intubated patients in intensive care unit (ICU) of Bahonar hospital in Kerman province, Iran during the year 2008. Tracheal samples were obtained from 111 intubated patients in the ICU by broncoalveolar lavage method. Amikacin, Ceftazidim and Imipenem were used to evaluate antibiotic susceptibility. For ...

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Detection of the Most Common Microorganisms and Their Resistance against Anti-microbials in Intubated Patients in an ICU in Kerman, Iran

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Detection of the Most Common Microorganisms and Their Resistance against Anti-microbials in Intubated Patients in an ICU in Kerman, Iran

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عنوان ژورنال:
iranian journal of pharmaceutical research

جلد ۲۰۱۰، شماره ۱۲، صفحات ۴۳۷-۴۴۳

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